Choline is a “building block” for the neurotransmitter acetylcholine, which promotes intelligence and memory in the brain…
Adequate choline intake is associated with preventing or resolving a number of diseases and conditions, such as Alzheimer’s, dementia, Depression, anxiety, memory loss, and Parkinson’s!
The consensus seems to be that CDP-choline may exert neuroprotective effects in an injured brain through its ability to improve phosphatidylcholine synthesis (Adibhatla and Hatcher, 2002). Choline also increases neurorecovery, which has led to its research as treatment for both stroke and TBI in animal models and in human clinical trials (Cohadon et al., 1982; Levin, 1991; Warach et al., 2000)
CDP choline was also shown to decrease Parkinson’s symptoms – (23% decrease in bradykinesis and 33% decrease in rigidity)- – study cited below
In humans, a choline-deficient diet also causes DNA damage and apoptosis (da Costa et al., 2006).
Too many studies to list, but I did include one below!
Bracco, F & Bergamasco, B & Bonuccelli, Ubaldo & Campanella, G & Saraceni, T & Deliberi, D & Gasparoli, E & Mancia, D & Piccoli, F & Monaco, P & Quattrone, Aldo. (2005). CDP-choline in the treatment of Parkinson’s disease. Giornale di Neuropsicofarmacologia. 27. 145-150.